Warfarin: changes to safety information

03 December 2009

Warfarin is used to treat dangerous blood clots in the circulation that could lead to major cardiovascular problems such as stroke. It has been in clinical use for over 50 years. 

The following report summarises a UK review of published literature, current practice guidelines and reports of adverse drug reactions for warfarin. 

As a result of the review, the safety sections in the product information for warfarin will be amended to give clearer, up-to-date advice.

This safety information has also been highlighted in the December 2009 issue of Drug Safety Update (page 7)PDF file (opens in new window) (403Kb).

This report presents the evidence that was available when the regulatory decision was made, showing a ‘snapshot’ of the clinical landscape at the time. However, any advice in this report remains current unless it is superseded by a more recent report (where relevant, this is indicated).

Page last modified: 11 February 2016