Statins: update to product safety information

This report was published in 2009. For more recent information, please see NICE guidance on cardiovascular disease: risk assessment and reduction, including lipid modification and the statins pages on NHS Choices

3rd November 2009

Statins are important medicines that are widely used to treat people with high levels of cholesterol and triglycerides (fats) in their blood. 

Lowering the body’s cholesterol levels reduces the risk of major cardiovascular problems, such as heart attacks or strokes.

This report summarises a Europe-wide review of clinical and scientific evidence, which found that any of the following side effects may occur with statins: sleep disturbances; memory loss; sexual dysfunction; depression; or interstitial lung disease (breathing problems).

This safety issue has also been highlighted in the November 2009 issue of Drug Safety Update: (page 11).PDF file (opens in new window) (225Kb)

This report presents the evidence that was available when the regulatory decision was made, showing a ‘snapshot’ of the clinical landscape at the time. However, any advice in this report remains current unless it is superseded by a more recent report (where relevant, this is indicated).

Page last modified: 26 May 2016