Neuroleptics and cardiac safety

01 July 2006

Antipsychotic drugs are mainly used to treat mental health conditions such as schizophrenia, agitation, severe anxiety, mania and violent or dangerously compulsive behaviour. Rarely, antipsychotics may cause serious side effects such as cardiac arrhythmias (irregular heart beat). 

A Europe-wide review of the effects of antipsychotics on the heart was completed in 2005. This public assessment report presents a summary of the review.

More information on antipsychotic medication can be found in the antipsychotic medication section of our website.

This report presents the evidence that was available when the regulatory decision was made, showing a ‘snapshot’ of the clinical landscape at the time. However, any advice in this report remains current unless it is superseded by a more recent report (where relevant, this is indicated).

Page last modified: 11 February 2016