Antipsychotics learning module

Contents

• 1. Introduction
• 1.1 Class members
• 2. Prescribing points
  • 2.1 Adherence to treatment
  • 2.2 Children and adolescents
• 3. Principal risks and risk-reduction measures
  • 3.1 Gastrointestinal adverse effects
  • 3.2 Central nervous system adverse effects
    • 3.2.1 Sedation and sleep disturbances
    • 3.2.2 Extrapyramidal side effects: introduction
      • 3.2.2.1 Extrapyramidal side effects: acute dystonia
      • 3.2.2.2 Extrapyramidal side effects: akathisia
      • 3.2.2.3 Extrapyramidal side effects: parkinsonism
      • 3.2.2.4 Extrapyramidal side effects: tardive dyskinesia
    • 3.2.3 Neuroleptic malignant syndrome
    • 3.2.4 Convulsions
  • 3.3 Cardiovascular adverse effects
    • 3.3.1 Blood pressure changes
    • 3.3.2 Cerebrovascular events such as stroke
    • 3.3.3 Cardiac rhythm disorders—QT interval prolongation
    • 3.3.4 Venous thromboembolism
  • 3.4 Metabolic adverse effects
  • 3.5 Hyperprolactinaemia and sexual adverse effects
  • 3.6 Blood disorders
  • 3.7 Temperature regulation
  • 3.8 Adverse effects on the skin
  • 3.9 Adverse effects on the eye
  • 3.10 Antimuscarinic adverse effects
  • 3.11 Dependence and withdrawal
  • 3.12 Important drug interactions
• 4. Precautions and risks associated with special uses of antipsychotics
  • 4.1 Elderly patients with dementia
  • 4.2 Pregnancy and breastfeeding
  • 4.3 Prolonged-release antipsychotic injections
  • 4.4 Antipsychotic injections for immediate effect
  • 4.5 Clozapine
• 5. Key points
• 6. Further information
• 7. Summary of licensed indications of antipsychotics for adults
• 8. Classification of antipsychotics
• 9. Structural formulae of selected antipsychotics
• 10. Self-assessment questions
  • 10.1 Feedback on self-assessment questions
• 11. Glossary
• 12. Module evaluation