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Safety information on medicines for healthcare professionals sent April 2007

Please note: In October and November 2010, the MHRA moved from its Market Towers address to a new location on Buckingham Palace Road. Please go to the contact us section of the website for updated contact details.

A list of letters sent to healthcare professionals in April 2007, to inform of new safety information and advice.

Date issued Product Safety information
02/04/2007 Mabthera (rituximab) Reports of progressive multifocal leukoencephalopathy in unapproved indications of systemic lupus erythematosus and vasculitis
11/04/2007 Pioglitazone-containing products (Actos, Glustin, Competact, Tandemact) Risk of fractures in women on long-term treatment
12/04/2007 Cabaser (cabergoline) Pathological gambling and increased libido are potential class effects of dopamine agonists

Risk of fibrotic cardiac valvuopathy: important information about second-line indication, contraindications, and new monitoring requirements
16/04/2007 Desmopressin Removal of primary nocturnal enuresis indication
17/04/2007 Ketek (telithromycin) Important information about restricted indications, contraindications, and safety measures
27/04/2007 Ventolin (salbutamol) New prescribing advice for obstetric use in the management of preterm labour and for use in respiratory disease


Page last modified: 07 February 2008