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Nephrogenic Systemic Fibrosis (NSF) and gadolinium-containing MRI contrast agents

Please note: In October and November 2010, the MHRA moved from its Market Towers address to a new location on Buckingham Palace Road. Please go to the contact us section of the website for updated contact details.

7 February 2007

Nephrogenic Systemic Fibrosis (NSF) has been associated with some intravenous gadolinium-containing magnetic resonance imaging (MRI) contrast agents in patients with severe renal impairment.

We have issued the following documents in relation to this safety issue.

Page last modified: 07 February 2007