Sterilization, Disinfection and Cleaning of Medical Equipment: Guidance on Decontamination from the Microbiology Advisory Committee to Department of Health

This publication, also known as the MAC Manual, has been prepared and endorsed by the MHRA's Microbiology Advisory Committee to provide advice on all aspects of decontamination.

Part 3 Procedures has been revised (June 2006).
Please note that this part is available only in electronic format . All future revisions of this manual will also be solely in electronic format.

Printed copies of parts 1 and 2 are available for £75 (free to UK health and social care providers). If you would like a printed copy, please contact us on 020 7084 3272 or e-mail: dts@mhra.gsi.gov.uk

Alternatively, you can download the text from the files below.

Part 1 Principles (revised 2002)
This part provides the general principles of decontamination, illustrated by some examples of basic decontamination equipment.

Part 2 Protocols (revised 2005)
This part contains the protocols for decontamination using cleaning, disinfection and sterilization processes. The introduction provides general guidance on the need for systems of work for the decontamination of medical devices and equipment both prior to clinical use and before inspection, service or repair. A general protocol for handling items to be maintained or repaired is then provided, and detailed protocols for cleaning, disinfection and sterilization follow this.

Part 3 Procedures (revised 2006)
Section 1  provides an overview of what the European Directives for medical devices mean for users. In particular, the implications of the Medical Devices Directive for those carrying out reprocessing activities will be reviewed, in terms of both self-declaration of compliance with the Regulations, and the information that reprocessors may expect to be provided with by manufacturers of CE-marked reusable devices.

Section 2  provides general procedures to be followed for particular groups of equipment including:

• Endoscopes
• Dental equipment
• Ophthalmic instruments
• Surgical instruments
• Ventilators
• Miscellaneous items