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Drug Safety Update: Volume 3, Issue 8, March 2010

Document details:

Type: Publication
Series No: 8
Audience: Healthcare professionals
Published: 9 March 2010
Format: Electronic and paper
Size: A4
Pages: 6
Price: Free
Author: MHRA
Copyright: Crown

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In this issue

Drug safety advice

  • Natalizumab (Tysabri): risk of progressive multifocal leukoencephalopathy increases after two years of therapy.
  • Fluoxetine: possible small risk of congenital cardiac defects, similar to that with paroxetine.

Stop press

  • Sirolimus: different immunoassays for therapeutic drug monitoring—risk of incorrect dose adjustment.

Other information from the MHRA

  • Drug Safety Update gains NHS Evidence accreditation.
  • MHRA conference for doctors in training.
  • Patient Information Leaflet of the month: Human Varicella-Zoster Immunoglobulin vaccine.

Page last modified: 09 March 2010