Please note: In October and November 2010, the MHRA moved from its Market Towers address to a new location on Buckingham Palace Road. Please go to the contact us section of the website for updated contact details.
In this issue
Drug safety advice
- Tacrolimus: new oral liquid (Modigraf); formulations not interchangeable without careful therapeutic monitoring.
Yellow Card Scheme update
- Problem with postal delivery of Yellow Cards.
Swine flu portal update
- Suspected adverse reactions to flu antivirals and vaccines confirm recognised safety profile.
Hot topics
- Orlistat safety update.
- Nicotine replacement therapy and harm reduction.
Stop press
- Sibutramine: suspension of EU licenses recommended as evidence indicates risks outweigh benefits.
- Off-label intraocular use of recombinant tissue plasminogen activator: risk of intraocular lens opacification.
- Please report suspected adverse reactions associated with intra-articular use of local anaesthetics.
Other information from the MHRA
- Patient Information Leaflet of the month: amoxicillin.
Drug Safety Update: Volume 3, Issue 7, February 2010 
