Rare and very rare, but potentially serious adverse effects
Antimuscarinic effects, such as visual disturbance, tachycardia and urinary retention, can occur with SSRIs but they are generally less marked than with tricyclic antidepressants (and in some cases are negligible).
Risk-reduction measures
In patients with prostatic enlargement or angle-closure glaucoma an antidepressant with negligible antimuscarinic effects should ideally be selected.
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